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February 2019: Cocaine Addiction

Dangers of Cut Cocaine

Cocaine is a powerful stimulant produced from leaves of the coca plant, native to South America. Today, Cocaine is a Schedule II drug which the DEA describes as highly addictive, with use potentially leading to severe psychological or physical dependence. Schedule II drugs are considered dangerous and are highly regulated, used only for legitimate medical purposes. 

Cocaine is also one of the most expensive illicit drugs. It can be altered or “cut” with other drugs or substances. The additive allows the seller to increase their profit and this can occur at any and all stages of the drug supply. The average purity of English Cocaine is reported to be no more than 20% to 30%. The BBC reported findings that almost 39% of cocaine tested was less than 10% pure. These additives can be incredibly harmful and have caused deaths. Below are details on the dangers and health effects of some of the most common agents used in diluting Cocaine. 

Phenacetin 

It is estimated that as much as 80% of Cocaine is cut with Phenacetin, a drug that was used as a pain killer in the United States until 1983. The drug was linked to the development of several types of cancers and pulled from the market globally. One study found that people who had abused phenacetin were four times more likely to develop bladder cancer. 

Levamisole

One of more dangerous and common additives found in Cocaine is Levamisole, a drug used by farmers to deworm livestock. The drug underwent clinical trials for treating cancer and autoimmune disorders and approximately 10% of patients patients in the trial developed agranulocytosis – a condition which has an effect similar to AIDS where the immune system is crashed catastrophically. A simple infection can become life-threatening without an effective immune system.  In 2011, U.S. Drug Enforcement Administration (DEA) estimated that 82%of seized cocaine contained levamisole, an increase from 1.9% in 2005.

Lidocaine, benzocaine, and procaine

These drugs are all anesthetics and numbing agents, often used to compliment the properties of Cocaine and give the impression greater quality (purity). Combining Cocaine and Lidocaine can be dangerous and lead to seizures and convulsions. 

Caffeine, Amphetamine, & Meth

These drugs are all cheaper stimulants, used to compliment the stimulant nature of Cocaine but are much cheaper ingredients. The caffeine compounds with the Cocaine to further strain the heart and cardiovascular system adding to the risk someone may have a heart attack.  

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Cocaine’s Effect on the Brain

Cocaine is a strong central nervous system stimulant which interferes with the re-absorption of dopamine to create a “high” from the surplus of positive chemicals in the brain. Normally dopamine is self-regulated in the brain and is recycled back into the cells that released it. When that re-absorption is disrupted by Cocaine, the flood of positive “feel-good” chemicals reinforces drug-taking behaviors

There are numerous studies and articles that talk about how Cocaine is highly addictive. Some may have read about the study where rats chose cocaine over food.  While it’s true that Cocaine produces an immediate euphoria, the drug affects other parts of the brain in ways that imprint the euphoria into memory. Cocaine affects the limbic system, which includes the area of the brain that acts as memory centers. Studies have shown, “when someone experiences a cocaine high, these regions imprint memories of the intense pleasure as well as the people, places, and things associated with the drug. From then on, returning to a place where one has taken cocaine or merely seeing images of cocaine-related paraphernalia triggers emotionally loaded memories and desire to repeat the experience.” 

Long-Term Brain Damage

Long-term Cocaine use has been linked to accelerated age-related decreases in grey matter in the brain – essentially accelerating the natural deterioration that occurs over time. 

Cocaine users may risk brain hemorrhage 20 years earlier than non-drug users. 

Abusing Cocaine may increase the risk of developing Parkinson’s Disease

NIDA supported researchers completed a study which found that Cocaine abuse resulted in long-term impaired mental and physical functioning including delayed memory, reaction time, and calculation ability. 

Frequently Asked Questions

What is Cocaine?

Cocaine refers to a drug derived from the coca plant native to South America. For thousands of years native people in South America would chew the coca leaves for their therapeutic stimulant properties. In the 1900’s Cocaine was used and developed as a painkiller. Today, Cocaine is a Schedule II drug which the DEA describes as highly addictive with use potentially leading to severe psychological or physical dependence. Schedule II drugs are considered dangerous and are highly regulated, used only for legitimate medical purposes. 

Either in powder or crystal form, Cocaine is often mixed with additives (some of which can be incredibly dangerous). It has become a common illegal drug with various street names including: blow, coke, crack, flake, icing, nose clams, snow, snow white, tardust, and white powder. “Crack” is the crystal form of Cocaine, which is normally a white powder. It is heated then smoked and received its street name from the crackling sound heard when heated. The differences between crack and cocaine are minor, although crack is generally viewed as more potent as it impacts the bloodstream more quickly resulting in a more potent although shorter lived high. This difference is due to how the drug enters the body, as opposed to chemical composition. 

How does Cocaine affect the brain?

Cocaine is a strong central nervous system stimulant which interferes with the re-absorption of dopamine to create a “high” from the surplus of positive chemicals in the brain. Normally dopamine is self-regulated in the brain and is recycled back into the cells that released it. When that re-absorption is disrupted by Cocaine, the flood of positive “feel-good” chemicals reinforces drug-taking behaviors

Long-term cocaine use has significant negative impacts on the brain including accelerated grey matter degradation, greater risk of brain hemorrhage, risk of developing Parkinson’s disease, and long-term mental and physical deficits. 

How addictive is Cocaine?

The Center for Substance Abuse Research very clearly states that when it comes to smoking crack cocaine, a person can become addicted after his or her first time trying the drug. While there are no shortage of articles about how cocaine is addictive, it primarily has this affect because of how the drug affects the limbic system in the brain. The limbic system contains the parts of our brian that hold the memory centers, and the euphoria experienced during the high is imprinted in the mind. Thereafter, returning to a place or even seeing images of cocaine can trigger memories and cravings

How is Cocaine addiction treated?

The majority of individuals seeking addiction treatment for cocaine are polydrug users meaning they use cocaine and additional drugs. While there are not currently any FDA approved drugs to treat cocaine addiction, therapy and clinical interventions can be effective. It’s also important to understand that frequent cocaine use has the affect of altering the mind and body, in some cases permanently. Specialized addiction treatment centers can help address individual, family, and social components, and provide treatment in a safe and sober environment which may be helpful for individuals who have tried to get clean on their own unsuccessfully in the past. Comprehensive addiction treatment centers also have the capability to address any co-occurring mental health disorder that may be contributing to drug use. 

Signs of Cocaine Use

Whether in a teen or adult, it’s important to see and understand the signs of Cocaine use. Cocaine is a short-lived drug with distinct symptoms while using and during the “crash”. Someone actively under the effects of Cocaine may exhibit some or all of the following symptoms:

  • Dilated pupils
  • Increased energy and alertness
  • Inability to remain still or general restlessness
  • They may exhibit a sense of invincibility or attitude that anything is possible 
  • Anxiety or paranoia 
  • Excited speech and/or increased heart rate
  • Irritability or heightened sense of aggression
  • Frequent sniffles or runny nose

The high is short-lived, approximately thirty minutes or less and even shorter if smoked. It’s equally important to recognize the signs of the proceeding crash which may include the following:

  • Decreased sense of smell
  • Hoarseness and trouble swallowing
  • Nosebleeds
  • Chronically runny nose
  • Change/decreased sleep pattern

If you or someone you love is suffering from Cocaine addiction, it’s important to receive treatment quickly to avoid the long-term negative effects Cocaine has on the lungs, heart, and brain. Contact us today to learn more about treatment options available. 

Quick Facts on Cocaine

2017 reported Cocaine use in the past month (0.8%), and lifetime use (14.9%) in the U.S. both increased compared to 2016 data. (SAMHSA)

 There were 13,942 overdoses involving Cocaine in 2017, more than double the 6,512 overdoses in 2007. (NIDA)

 The 2018 Monitoring the Future Study reported 3.9% of twelfth grade students had used cocaine in their lifetime, 2.3% in the last year, and 1.1% in the last month. (NIDA)

In 2017, an estimated 2.2 million people aged 12 or older were current users of cocaine. (SAMHSA)

Almost 15% of people ages 12 and older have tried Cocaine in their lifetime according to the National Survey on Drug Use and Health in 2017. 

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